The process of freeing trade that has been occurring in the country since the late twentieth century has uncovered a number of weaknesses and threats facing our business organizations these days, in particular for small and medium enterprises (SME). The overall objective of this research is to analyze the relationship between the Commercial Management system and competitiveness of industrial and agroindustrial SMEs in Tundama, Colombia, in order to generate viable recommendations to give these business organizations competitive advantages; the methodology used was based on a descriptive non-experimental methodology design. Notably, the business organizations studied in this research have high transaction costs when accessing input markets and services, which constitute a major obstacle to advancing technology adoption.