Although Colombia has several drug information services and centers, there aren't studies about the information requests to this institutions. This is a retrospective and descriptive study, conducted with data from the requests for passive information to the Drug Information Service of the San Ignacio University Hospital in Bogotá, since April 2010 until December 2011. There were 197 requests for information, equivalent to 9 per month; and 232 questions, equivalent to 11 per month. 79.2% of requests were resolved the same day of consultation. 77.2% of the consultants were nurses. 69% of requests were made by health services. The Office of Medicines not included in the Mandatory Benefit Plan was the service that most queries made. The stability, the administration and preparation of drugs were the most frequently consulted. 38.6% of consultations were conducted by telephone and 67.0% were answered by email. The study concludes that the service productivity was similar to that in other institutions but there are differences in volume of questions, consultants and communication ways.