In order to assemble a hematological characterization 25 females (F; 758,4±362,5 g of weight and 60,5±0,7 cm of total length) and 12 males (M; 577,1±187,1 g y 49,8±4,9 cm) of Trans-Andean shovelnose catfish adult Sorubim cuspicaudus, captured in the Sinu river basin were examined. The total erithrocytes were of 8,3±2,0x10 6 F and 9,7±3,2x10 6 cel/mm 3 M, thrombocytes 7,4±4,3x10 5 cel/mm 3 F 3,5±2,4x10 5 cel/mm 3 M and leucocytes in F were estimated in 53±39x10 3 cel/mm 3 and 43±16x10 3 cel/mm 3 in M. The differential count of leukocytes for