Patient that arrived to the emergency room with intense upper abdominal pain associated to abdominal distension, nausea and emesis of alimentary content, symptoms that begun five months before The patient referred some episodes of liquid diarrhea (neither mucous nor bloody), hyporexia, asthenia and adynamia that became progressive until limitation of his physical activity, taking him to prostration in bed and caquexia. The day before the consult he presents with melanemesis and vomit with total intolerance to the oral intake, associated to diarrheic dark stools which took him to the emergency room. During the diagnostic evaluation a severe gastroduodenitis due to a Strongyloides infection is evidenced, which is documented by gastric and duodenal biopsies. The patient also has an associated infection of HTLV-1 virus. With the diagnosis of a strongyloides hyperinfection, a treatment with ivermectine is started, with complete resolution of the symptoms. After showing the case in detail, we make a review of the literature about the treatment of this parasitic infection and its association with HTLV-1.