Resumen Introduccion: Los adultos mayores por sus condiciones biologicas y sociales se consideran vulnerables, al vivir en situaciones de riesgo determinadas por los recursos personales, economicos, del entorno, familiar, comunitario, y de acceso a los servicios de salud. Objetivo: identificar los factores personales y del entorno asociados a la vulnerabilidad de la poblacion mayor con alteraciones de salud en municipios del Departamento de Narino. Materiales y metodos: Se realizo un estudio descriptivo correlacional con una muestra de 384 adultos mayores pertenecientes a 19 municipios del Departamento de Narino, agrupados en cinco regiones. Mediante una regresion logistica se identifico la relacion que existe entre los factores personales y del entorno con la vulnerabilidad. Resultados: Se encontro que tienen mayor probabilidad de ser altamente vulnerables, los adultos mayores de la region occidente (OR=3.80 IC 95% 1.34-10.78), con hipertension arterial (OR=2.64 IC95% 1,07-6.53) y que no tienen cuidador (OR=2.52 IC 95% 1.45-4.54). Conclusiones: Los factores de riesgo que hacen mas vulnerables a los adultos mayores son: vivir en regiones deprimidas economica, social y geograficamente apartadas, no contar con el acompanamiento de una persona para su cuidado y tener hipertension arterial, variables que se deben tener en cuenta en la prestacion de los servicios de salud y en la asignacion de recursos para la proteccion de un grupo poblacional que necesita que se rompa la cadena de la inequidad y la desigualdad social.Abstract Introduction: Older adults are considered vulnerable because of their biological and social conditions- situations of risk determined by their personal, economic, family, community resources, environment, and access to health services. Objective: To identify the personal and environmental factors associated with the vulnerability of the population with health alterations in the municipalities of the department of Narino. Materials and methodos: a correlational descriptive study with a sample of 384 older adults from 19 municipalities in the department of Narino, who were grouped into five regions was performed. The relationship between personal and environmental factors to the vulnerability was identified using logistic regression. Results: It was found that older adults from the western region (OR = 3.80 95% CI 1.34-10.78), with arterial hypertension (OR = 2.64 95% CI 1, 07-6.53) and those who have no caregiver (OR = 2.52 95% CI 1.45 -4.54) are more likely to be highly vulnerable. Conclusions: The risk factors that make the elderly more vulnerable are: living in remote regions that are economically, socially and geographically depressed, not having the support of a person for their care and having high blood pressure. These are variables to be taken into account in the provision of health services and the allocation of resources for the protection of a population group who needs that the chain of inequity and social inequality to be broken.