Objetive: to determine the prevalence and behavior of musculoskeletal pain in workers handling and loads up in an airport services and specialist courier company by applying Nordic Questionnaire. Materials and Methods: It was conducted a descriptive study. Nordic Questionnaire was administered to 74 men of 98 cargo handlers an airport services company, with no limit on work time or age. We assessed working conditions for ergonomic risks. The data was analyzed using SPSS® version 16.0, obtaining frequency distributions for qualitative variables, in addition to obtaining measures of central tendency and dispersion for quantitative variables. Results: It was found that the prevalence of musculoskeletal pain in the study population was 88% (65 workers). 42 workers had pain in more than one body segment and 23 in only one. The lumbar region had the highest prevalence with 70% (52 cases) followed by wrists / hands with 30% (22 cases) and neck with 28% (21 cases) in the same period. Conclusions: It is recommended, among other actions, to generate control measures in the individual and the work environment as active and frequent training of workers who are exposed. It is also recommended to create tools to improve the cargo handling system and work teams that reduce physical exertion.