The anatomical and epidermal characteristics, as well as the physiological response, of 'Colombia' ecotype cape gooseberry plants treated or untreated with foliar applications of kaolin at 2 irrigation levels (well-irrigated plants vs. water-stressed plants) were evaluated. Relative Water Content (RWC), stomatal density, and chlorophyll index were reduced under water stress. Water stress increased leaf temperature and trichome density. In water-stressed plants, the foliar application of kaolin decreased transpiration rates, leaf temperature, trichome density, and leaf thickness. Kaolin also improved the plant height, total plant dry mass, water-use efficiency, and increased stomatal density in water-stressed plants. The results suggest that kaolin may be a useful tool to mitigate the negative effects of water stress and may improve the efficient use of water in cape gooseberry plants with especial water conditions. Keyword: Leaf characteristics, Leaf transpiration, Water stress.