This work studied the phenolic content, antioxidant activity and the content of vitamin C in different stages of maturity of the fruits of three varieties of guava in Colombia. We worked with two wild varieties, the regional red (RR) and white regional (RB) and a promising character as is the variety guavata victory (GV), all from the Suarez River region (Santander, Colombia). Ethanol extracts were obtained and evaluated free phenol content, antioxidant capacity by ABTS and DPPH, FRAP, bleaching of b-carotene and vitamin C by HPLC. The RB when ripe showed higher value of free phenolic content and antioxidant capacities and best RR was the one with higher value of vitamin C. . Vol17-3D_Maquetacion 1 2/12/12 16:14 Pagina 611