The stratigraphy of the Chipaque Formation, Guadalupe Group, Guaduas Formation and Socha Inferior Formation in the vicinity of San Luis de Gaceno is discussed here. The Guadalupe Group from the Llanos Foothills is divided in three new litostratigraphic units that from base to top are named Arenitas de San Antonio Formation (Guadalupe Inferior, early Campanian), Lodolitas de Aguacaliente Formation (Guadalupe Medio, late Campanian) and Arenitas de San Luis de Gaceno Formation (Guadalupe Superior, early Maastrichtian). The units that have the same stratigraphic position of the Guadalupe Group and are consequently bounded by the same discontinuities, are included in an allostratigraphic unit named Guadalupe Allogroup. This unit is in turn divided in the Alloformations Guadalupe Inferior, Guadalupe Medio, and Guadalupe Superior. In the same way, the units bounded by the unconformities of the late Paleocene and late Eocene, are included in the Alloformations Socha Inferior (late Paleocene) and Socha Superior (early Eocene) of the Socha Allogroup. In addition, the palynology, biostratigraphy, and sedimentary environments are discussed. The succession is divided in sequence-stratigraphy units in order to provide a regional correlation frame. The sequences, that are bounded by unconformities or correlative surfaces between sea level falls, are named SK5 (uppermost interval of the Une Formation and Chipaque Formation), SK6 (Arenitas de San Antonio and Lodolitas de Aguacaliente Formations), SK7 (Arenitas de San Luis de Gaceno Formation and lower part of the Guaduas Formation), and ST2 (Socha Inferior and Socha Superior Formations). Finally, a discussion of the implications in petroleum exploration is presented in the light of the stratigraphic, sedimentologic, and geochronologic framework proposed here.