This paper presents the results that have been obtained in an investigation in the first person medical students of the Medicine Program at the Universidad Libre Barranquilla Campus. The research was aimed to assess the level of knowledge and attitudes about STIs. The study is based on analysis of a mixed questionnaire with structured questions and narrative, consisting of a sample of 365 students of the ten semesters. The results show that most of the population is female and single marital status. Participants have a high degree of knowledge of STIs, directly proportional to the increase in the level semester, which indirectly indicates that the theoretical knowledge acquired in the different subjects of the curriculum medicine program, but in the attitude disease there is a cognitive dissonance between the information received and the attitudes.