This article presents the revision and analysis of several studies that address the categories behaviors and unsafe sex to engage in a reflection of the main findings under the gender perspective. On this basis, points of divergence and convergence of research were established, leading to a reflective dialogue that suggests the recognition of social and historically constituted power relations, their impact on social reality and the relationship between contemporary men and women. Finally conclusions are presented reflecting meanings attributed to femininity, masculinity, body and sexuality, which is exposed as an invitation to consider the approach to address intervention programs that promote health and reproductive rights of young people.