Abstract Streptococcus equi subsp. equi is the causative agent of Strangles in horses, the most common respiratory infectious disease worldwide. Typical signs of the disease are fever, nasal, discharge, abscessation of retropharyngeal lymph nodes and inappetence; complications as Bastard Strangles and Purpura haemorrhagica may occur. Outbreaks may last for months or even years in farms and stables causing a great economical impact due to the large periods of convalescence, quarantine and treatments. Some horses suffer guttural pouch empyema, harbouring the bacteria in pus or chondroids, becoming carriers, which are a major problem for the prevention. Currently, many research groups all over the world are focus on the production of a safe and effective vaccine against this highly contagious disease. The control of the disease is difficult without a highly effectiveness vaccine. In Colombia, there is not well known the prevalence of Adenitis neither the microorganisms involved in this disease; moreover, in some countries of Latin America the carrier prevalence is markedly underestimated or unknown and it is necessary to focus more resources and effort to epidemiology studies in this disease.