Resumen Objetivo: Relacionar los factores de riesgo cardiovascular en personas de 20 a 79 anos con variables sociodemograficas, antropometricas, clinicas y categoria de riesgo coronario duro a 10 anos de la ciudad de Manizales. Materiales y metodos : Estudio descriptivo correlacional. Muestreo no probabilistico, muestra 405 personas de la ciudad de Manizales, que firmaron el consentimiento y cumplieron los criterios de inclusion. Se realizaron entrevistas, mediciones antropometricas y en sangre de colesterol total y HDL. Resultados: Existio asociacion estadisticamente significativa p<0,05 y fuerza de asociacion alta (coeficiente mayor de 0,6) en la edad con el riesgo coronario segun tension arterial y tratamiento antihipertensivo. En las variables antropometricas el peso, el indice de masa corporal con el riesgo coronario segun hipertension arterial, colesterol total, colesterol HDL y obesidad abdominal. En las variables clinicas el tratamiento antihipertensivo con el factor de riesgo de hipertension arterial. Conclusiones : Existe predominio de factores de riesgo modificables tanto antropometricos como clinicos. La edad y el valor de colesterol total en la poblacion encuestada representan riesgo mayor en mas del 50% de los participantes. Dentro de los factores predisponentes el sedentarismo fue el mas comun. La categoria de riesgo coronario duro a 10 anos latente fue la de mayor frecuencia. Abstract Objective: To relate cardiovascular risk factors in people aged 20 to 79 years with sociodemographic, anthropometric and clinical variables and hard coronary risk category to 10 years in the city of Manizales. Materials and methods: A descriptive correlational study. Non-probability sampling. The sample were 405 people in the city of Manizales, who signed the consent and met inclusion criteria. Interviews, anthropometric and blood total cholesterol and HDL measurements were made. Results: There was statistically significant association p <0.05 and strength of high association (higher coefficient of 0.6) in the age with coronary risk according to blood pressure and antihypertensive treatment. The anthropometric variables were weight, body mass index with coronary risk as high blood pressure, total cholesterol, HDL cholesterol and abdominal obesity. The clinical variable was antihypertensive treatment with the risk factor of hypertension. Conclusions: There is predominance of modifiable anthropometric and clinical risk factors. Age and total cholesterol in the population surveyed represent greater risk by more than 50% of participants. Among the predisposing factors sedentary lifestyle was the most common. The category of hard coronary risk at 10 years was the most latent frequency.