A prominent positive free-air gravity anomaly mapped over a roughly 50-km diameter basin is consistent with a mascon centered on (4°30'N, -69°15'W) in the Vichada Department, Colombia, South America. The inferred impact crater is nearly one third the size of the Chicxulub Crater. It must have formed recently, in the last 30 m.a because it controls the path of the Vichada River. The impact crater structure has been partially eroded and is almost completely covered by vegetation. No antipodal relationship has been established. The proposed impact appears to have contributed to the development of mineral deposits of economic interest. The impact shock waves extensively thinned and disrupted the Precambrian cratonic crust. Athick sedimentary cover, dense vegetation and erosional processes greatly limits direct geological testing of the inferred impact basin. Ground follow up gravity and magnetic surveys are recommended for confirming the regional free air gravity anomalies.