Introduction: Disc disease is one of the most common causes of lumbar pain. The new era of treatments for degenerative disc disease involves the use of minimally-invasive thermal technologies allowing for collagen remodeling and destruction of nociceptors in the annulus. Howev- er, a better understanding of the treatment patho- physiology is needed. The purpose of this study was to measure intradiscal temperature variation after thermodiscoplasty. Material and methods: A human cadaver spine specimen was obtained and divided into blocks, each composed of two inter- vertebral plates and an intact disc. Radiofrequen- cy was applied at five spots with three different time intervals. Temperature was measured in each of the combinations. Units were weighed before and after treatment. Finally, the disc was exposed and the tightening achieved with each radiofre- quency application was measured. Data were ana- lyzed with the SPSS software. Results: The mean weight reduction obtained was 1.4 g on average (SD 0.599), with values between 0.5 and 2.6 grams. Mean temperature in the posterior rim of the an- nulus was 37.6 o C and mean temperature variation