This article describes a 47 years old patient's case carried to urgency and was diagnosticated and trated as a clinical frame of epigastric abdominal pain, aciopeptic illness and suspected a grastrointestinal bleding. He died, and during the autopsy, it was found a thrombosis and a rupture of the upper mesenteric artery. The mesenteric thrombosis death rate is about 75%. The treatment is difficut, and generally, patients need a surgery. Principally, we observe this kind of thrombosis between the 5th and 6th decades of life. Frequently, it has a base disease. The mesenteric ischemia may be caused by an emboli or a thrombosis of the upper mesenteric artery, or it may be a not occlusive isquemia, or a mesenteric vein thrombosis. The rupture of one artery as the mesenteric, specially at this patient's age, is usually caused by arteriosclerosis that includes sorne complications as the thrombosis. In the texts reviewed, any case that describes the thrombosis in an associated way to the rupture of the upper mesenteric artery was found.