BACKGROUND: previous studies have demonstrated that enamel matrix derivative has the ability to improve clinical parameters. OBJECTIVE: to compare the results obtained in relation to probing depth, clinical level attachment and keratinized tissue when applying Emdogainfi plus connective tissue graft (CTG) with coronal advanced flap (CAF), with CTG with CAF like unique treatment, in gingival recessions Miller·s type I or II to verify if Emdogainfi improve coverage of gingival recessions. METHODS: this randomized controlled clinical trial, split mouth, was made in 16 sites with gingival recessions bilateral Miller·s class I, selected at random for the experimental group (Emdogainfi and SCTG). The contralateral tooth was assigned to the control group (SCTG). Measurements at the beginning and three months included: gingival margin, probing depth, clinical attachment level and keratinized tissue. The data were analyzed with U Mann-Whitney test, Fisher test and Wilcoxon test; and was taken a significance from p£=0.05. RESULTS: results for both the test and control groups were similar for all measured clinical parameters. Both treatments showed to be effective with root coverage (RC). The percentage average of RC in the group control was of 100% and for the experimental group was of 87.5%. Although there were better results in the control group the differences between both groups were not statistically significant (p=0.077). CONCLUSIONS: based on the results of this investigation, the addition of Emdogainfi to SCTG with CAF it significantly does not improve the clinical results.