We present the clinical case of a woman aged 51 years, inveterate smoker, with antecedents of anemia of several years of evolution and personality disorders treated with phenothiazines, referring recurrent episodes characterized by moods disorders with melancholic elements which began a month ago. These problems were perceived by her coworkers, but they did not give importance to that until one day the patient awaked with a left hemiparesis. An image of a cerebral tumor was found by axial tomography assessed by Neurosurgery, and subjected to conservative treatment with radiation by that specialty. After she got better, the patient was discharged until she returned to hospital two months later with fever lasting 12 days, deciding her readmission in the Matanzas military hospital. The patient died and it was found a right renal adenocarcinoma, poorly differentiated with multiple cerebral metastases in the autopsy.