La ingenieria de tejido oseo surge como una nueva opcion para el tratamiento de muchos tipos de afecciones, entre ellas las enfermedades oseas, permitiendo resolver multiples problemas en el area medica. El desarrollo de una matriz de hidroxiapatita para cultivo de celulas oseas permitira contar con otra alternativa para enfrentar las enfermedades causadas en el hueso y articulaciones que frecuentemente llevan a la discapacidad en las personas. En este trabajo se obtuvo hidroxiapatita sintetica por la ruta de precipitacion a partir de fosfato de amonio NH4H2PO4 y nitrato de calcio Ca(NO3)2.4H2O. Se formaron matrices en las cuales se indujo macroporosidad con el agente natural Zea mays, con particulas entre 350 µm y 600 µm, y microporosidad con celulosa en proporciones peso/peso de 4% y 8%. Las muestras fueron caracterizadas con pruebas de compresion, microscopia electronica de barrido (SEM), que incluyo espectroscopia por dispersion de energia de rayos X (EDS) y difraccion de rayos X (DRX). Se obtuvieron matrices macroporosas de hidroxiapatita cristalina con un diametro de poro entre 300 µm y 500 µm en promedio, con porosidades entre 35,85% y 45,61%, densidades en el rango de 1,48-1,77 g/cm3 y relacion Ca/P de 1,7. Para los bloques con 4% de agente microporoso la resistencia a la compresion fue de 1,06 MPa y el modulo de elasticidad, de 67,15 MPa. Los bloques con 8% tuvieron una resistencia a la compresion de 1,08 MPa y un modulo de elasticidad de 54,65 MPa. Abstract: Bone tissue engineering came up as a new option treatment for different kinds of illness, among them bone diseases. All this development has allowed solving multiple medical problems. The development of a hydroxyapatite scaffold for bone cells culture will be another alternative to attend several diseases that are caused on bones and that usually lead to disabilities in people. In this study synthetic hydroxyapatite was produced by a precipitation route with amonium phosphate (NH4H2PO4) and calcium nitrate (Ca(NO3)2*4H2O) as precursors. Scaffolds were manually molded, and macroporosity was induced with a natural agent, named Zea mays, with a particle size ranging between 350 µm and 600 µm. Microporosity was induced using cellulose with proportions of 4% and 8% (weight/weight). The samples were characterized by compression test, scanning electronic microscopy (SEM), energy dispersive spectroscopy (EDS), and X ray diffraction (XRD). Crystalline hydroxyapatite scaffolds were obtained and they presented an average pore diameter between 300 µm and 500 µm, porosities between 35,85% and 45,61%, densities in the range of 1,48-1,77 g/cm3 and Ca/P ratio of 1,7. The calculated compressive strength for the 4% of microporous block was 1,06 MPa and the elastic modulus was 67,15 MPa; while the 8% microporous blocks showed a strength of 1,08 MPa and an elastic modulus of 54,65 MPa.