Resumen El Sindrome Hellp es descrito como una enfermedad ocasional en la que ocurre hemolisis, enzimas hepaticas elevadas y trombocitopenia en pacientes con preeclampsial severa. Aunque las caracteristicas del Sindrome Hellp pueden ser similares a las de la preeclampsia severa, muchos estudios han reportado algunas diferencias en su presentacion clinica. Se hizo una revision del numero de casos de Sindrome Hellp en el servicio de gineco-obstetricia de nuestra institucion, y encontramos 8 casos de abril a diciembre del 2005, lo que nos estimulo a revisar esta patologia debido al incremento de su presentacion. El objetivo de este caso clinico fue revisar factores de riesgo, curso clinico, manejo y hacer enfasis en la importancia del control prenatal en un caso presentado en el Hospital Universidad del Norte. Palabras claves: Sindrome Hellp, trombocitopenia, factores de riesgo, preeclampsia, embarazo, alto riesgo obstetrico / SALUD UNINORTE. Barranquilla (Col.) 2006; 22 (2): 188-194 Abstract The Hellp syndrome is described as an occasional disease where a combination of hemolysis, elevated liver enzymes, and thrombocytopenia is displayed in patients with severe gestational hypertension. While many features of Hellp syndrome may be similar to severe preeclampsia, several studies have reported some differences in their clinical presentation. A casesreview of Hellp syndrome was performed in gynecology and obstetric service. Eight cases were found from april to december of 2005, which stimulate to review this pathology. The aim of this clinic case was to review the risk factors, the clinic course and the management, with an emphasis on the importance of prenatal care in a case presented in Universidad del Norte Hospital. Key words: Hellp syndrome, thrombocytopenia, risk factors, preeclampsia , pregnancy, high risk pregnancy