Most of the species have a heterogametic male XY and a homogametic XX female chromosome. In male XY chromosomes there are only some regions that mantein information interchanges between the Y and X chromosomes (Xpter and Y pter) during meiosis, which is called the pseudoautosomic region. There has been put toward a hypothesis that the chromosome Y is derived from chromosome X, and that formerly they were homologous in all its extention. Possible implied mechanisms of this biological mechanism in this evolutive process are DNA fragments that can move through the genome. This are called movable genetic elements. Based in studies the genes of the cuticula larval (Lcp) of sexual chromosomes of Drosophila Melanogaster, D. Permisilis, D. Seudooscura and D. Miranda have given evidence of the movable genetic elements. The molecular analyses made in D. Miranda are a clear scientific evidence of how an event of chromosomal translocation associated to natural and