The main extracellular constitutes a macromolecules group, located on the outside of the cells that on the whole will form the ecosystem where the cell will carry out its vital functions: multiplication, preservation, biochemical processes and indispensable physiopathologics for the survival of the vital fabrics of the alive organisms and the survival of the different species. These molecules are synthesized by the same cell or they come from the bloodstream. They are four the macromolecules committed in their formation: System collagen, elastic system, glicosaminoglicanos and glicoproteinas of adhesion.