Know the experience in the use of self-expanding metal stents for the management of malignant obstructions of gastric outlet or colon, and describe the clinic, demographic and pathological characteristics of patients from the National Cancer Institute (NCI) during the period from January 1, 2010 and September 30, 212. Methods: observational , descriptive, retrospective study of case series that included patients with gastric outlet tract obstruction or colorectal. The clinical characteristics and the factors involved in the technical and clinical success of inserting SEMS are analyzed and the influence of such devices in morbidity and mortality. Results: The study included 96 patients, 23 with colorectal SEMS and 73 with duodenal SEMS. Mean age 63.7 years. The most common symptoms were nausea (74%) and vomiting (65.6 %). Of the 96 patients, 62.5 % had metastases at the time of the procedure. In 90 patients (93.7%), a single stent were used while in 6 patients (6.3%) two stents were used. In 81 patients (84.4 %) the goal was palliative and in 15 patients (15.6%) was pre- cancer therapy. Technical success for insertion of duodenal SEMS was 97.2 % and clinical success was 93.1 %. For colorectal SEMS, technical and clinical success was 91.3%. Was eight complications: two perforations, one obstruction, one fragmentation and four migrations. Three patients required surgery to resolve a complication. The average life expectancy after the procedure was 102 days for duodenal stent and 159 days for colorectal stent. No mortality was presented secondary to the procedure. Conclusions: Insertion of SEMS is a minimally invasive procedure that has proven to be an effective palliative treatment and an alternative to reduce the formation of ostomy, complications and reducing costs. As a bridge to surgery, the prosthesis may decrease the high morbidity and mortality associated with emergency surgery.