Objective: To determine ethanol, acetaldehyde and methanol concentrations in guarapo consumed by patients with alcoholic hepatic cirrhosis in the Colombian State of Cundinamarca. The study was performed at La Samaritana University Hospital in Bogota D.C. and 41 villages of the Province of Cundinamarca, National Institute of Legal Medicine and Forensic Sciences at Bogota D.C Methods: Phase one: Retrospective survey of clinical records of patients with alcoholic hepatic cirrhosis due to chronic consumption of guarapo seen in La Samaritana University Hospital in Bogota Phase two: Collection of guarapo samples in the villages identified and chemical analysis by means of high performance gas chromatography Results: All samples showed ethanol concentrations in the range of 0,50 % to 6,94%. In 41 of them acetaldehyde was present in variable concentrations. None of them were positive for methanol. The samples with the higher ethanol concentrations came from Gualiva, Rionegro and Tequendama, which are the provinces with the higher number of patients with alcoholic hepatic cirrhosis seen in La Samaritana University Hospital. Conclusions: Guarapo is the national typical drink, and it has significant concentrations of ethanol. Its consumption in high quantities and for long periods of time exceeds largely the toxic limits associated to the development of hepatic cirrhosis.