The interaction between hydroxyapatite, bioactive glass and polylactic acid was evaluated, which were synthesized by aqueous precipitation methods, sol - gel and polycondensation respectively, and they were characterized by FTIR, XRD, DSC. Samples with different percentages of polymer and ceramic were obtained to study their ability to adsorb phosphate, and later to identify which of these samples of materials present a better response to osseointegration in the presence of simulated body fluid. Samples were immersed in that fluid with different relations of Ca/P and their adsorption capacity was evaluated by EIS. The electrochemical parameters obtained allowed to estimate the resistive and capacitive elements of an equivalent circuit linking the thermodynamic parameters associated with adsorption phenomena experienced. Finally, the amount of adsorbed ions was determined by AAS.