This paper analyzes the impacts of spatial and temporal aggregation of empty trips models. The authors analyze five models of empty trips (Noortman and van Es, and four Holguin-Veras and Thorson empty trips models) for different aggregation levels of six national freight origin-destination (OD) matrices. They were collected by Colombia's Ministry of Transportation during the 2000 to 2005 time period. The research includes an assessment of the spatial aggregation and time-dependency of the parameters for the different models. Furthermore, three aggregation levels are examined to study the performance of the different empty trips models specifications and the spatial and temporal stability of the parameters for these models.