From the protection of the environment, the problem of the residuals squatter a main place in the environmental administration; presently study a test pilot was standardized, to characterize the toxic waste generated in the production of detergents, to standardize methods of chemical valuation and microbiologica of polluted waters that allow later on to apply methods of biological purification and processes of biotratamiento of residuals, the project macro of handling of toxic waste it was addressed this way in small and medium companies producers of detergents. The presence settled down of toxic in the studied waste, represented in surfactantes significant amounts, phenols, hydrocarbons, fat and phosphates and the decrease of its quantity in front of the action of bacterias, situation that allowed to conclude that the approach to the biotransformacion process could be carried out.