In the study of the microorganisms associated with the bud rot (PC) disease of the oil palm in Colombia, it was possible to isolate, identify, purify, growth in artificial media and develop pathogenicity test of the different agents that according with the literature and the experience of the research team might be associated with the disease. These studies indicated that the PC is not started by Fusarium sp. , Colletotrichum sp. , Pestalotia sp. , Rhizoctonia sp. , Thielaviopsis sp. , Nigrosposa sp. , Curvularia sp. , Alternaria spp. , Helminthosporium spp. , Diplodia sp. o Lasiodiplodia sp. , as well as with bacteria of the genus Erwinia or Pseudomonas, all of them observed frequently in advanced stages of the disease. The symptoms of the disease were not reproduced when oil palms were inoculated with different isolates of these fungi or bacteria.