In 2007, the Declaration of Mexico for Attention Deficit Hyperactivivity Disorder (ADHD) was developed by a group of specialists in mental health and neuroscience. This statement summarizes the most recent scientific information about the disorder. In 2009, during the III Latin-American Consensus on ADHD, the Cartagena’s Declaration for ADHD was issued, which updates scientific information and promotes a campaign against ADHD stigma in society and schools. A draft document was developed before the meeting and reviewed by participants at the Consensus. This paper was checked by twenty-six experts from ten different countries from the region. Twenty-seven points of the statement about clinical, epidemiological and therapeutic topics were listed, based on newest scientific evidence for ADHD. The Cartagena Declaration for ADHD is the second call that Latino-America League for the Study of ADHD (LILAPETDAH) members performed as an organized and multinational group, to increase knowledge on clinical manifestations and treatment of ADHD and to promote joint efforts and social strategies aimed to reduce stigma of this disorder