Contemporary arguments showing the characteristics of a subjectivity conception from a historic-cultural perspective are presented, taking in account its conceptual transition from the personality psychology toward the social psychology, and its intersection with the sociology and the philosophy of the subject. The concepts of subjective sense and subjective configuration as a sense qualification category are developed in the document and constitute the starting point for a reflection about the politic subjectivity and the ways to research it, considering the qualitative epistemology, which is based on the constructive interpretative nature of knowledge.