In this text, the history of rural possessions belonging to the Mompox school in 1767 is developed, according toinformation found in the manuscript “Mompox School, extract from the edicts of its occupation, 2nd of July 1767”,document that is nowadays under custody of the Historic National Archives in Madrid, Spain. The manuscript offers adetailed list of the different estates, their acquisition due to donations, purchases or exchanges, their geographicallocation, their primarily economic vocation, their spatial components and architectural program. It also provides a listof the slaves employed in the estates, the tools or utensils, animals and stables. This study enables the verificationof a regional spatial articulation between the Jesuit school located in the central area of the town of Santa Cruz deMompox, and its rural possessions –important rural productive enclaves that represented the authentic economicalsupport for the school–, strategically located throughout the course of the Magdalena river.