Tocotrienols (T3E), besides being antioxidants exhibit hypocholesterolemic effects. They are in palmolein and some cereals. Objective. Define the role that dietary T3E could have on lipid profile and oxidative capacity of LDL. Materials and Methods. We determined the fatty acid profile and the concentration of T3E on ingredient and diets. Rabbits were maintained on diets with and without T3E for 4 months. Young women consumed diets high and low on T3E for a month. Monthly, lipid profile was determined. Oxidative capacity of LDL was determines at the end of the treatment. Results. MUFA or PUFA treatments without T3E produced beneficial effect on total cholesterol and LDLc levels, but decreased HDLc. Treatment with SFA and natural source of T3E, did not produce a marked effect on total cholesterol and LDLc levels and improved HDL levels. By including T3E to diets with cholesterol, we observed a beneficial impact on lipid profile parameters. The T3E exert a beneficial effect on the oxidative capacity of LDL. Conclusion. The inclusion of dietary T3E,regardless of its source, appear to decrease or maintain neutral serum cholesterol levels and limit the increase of it when dietary cholesterol is added. They also have a beneficial impact on HDLc levels and the oxidative capacity of LDL.