Objective: Study carried out between the years 2009 and 2010 in the cities of Barranquilla and Sincelejo that has as main objective to determine the microdeletions in the DAZ region of the Y chromosome in infertile men. Materials and Methods: study was developed with a sample of 33 men, selected in specialized consultation, previous confirmation of infertility through spermograms studies. Seventeen STSs were analyzed from different azoospermia regions in addition to the SRY, the DS271 and the Kaly gene. DNA extraction from peripheral blood through Bio-mol protocol, PCR multiplex master Como citar este articulo: Gonzalez G, Silvera C, Vasquez JF. Microdeleciones de regiones AZF del cromosoma Y e infertilidad. Biosalud. 2013;12(2):9-23.