This article is based on the idea that, in Colombia, infant subordination was used as a biopolitical mechanism and an anchor of the colonial difference. Based on epistemological and methodological references which articulate poststructuralist archeology and some positions of the de-colonialist turn, two moments in which particular forms of subjectivity in children are proposed. The first (1920-1936) is characterized by the speech and mechanisms associated with organic degeneration of infants. The second (1936-1968) introduces socio-cultural de-generation, progress and rights as a discursive and strategic substrate on which the administration of the social body is processed, by means of the child. Finally, analytical criteria are suggested to continue investigating these forms of governability from infancy.