Translation from Spanish to English by T.A. Zuur and The Language Workshop Received: 25-03-11 Accepted: 02-08-11 Abstract We report the case of a patient with cecum ameboma, an uncommon intestinal manifestation of amebiasis. Patient underwent surgery after an initial diagnosis of a perforated cecal neoplasm of an appendiceal adhesion mass. Histology confi rmed the presence of trophozoites of E. Histolytica in an area of ulceration and necrosis of the cecum wall. While initially the ameboma was treated medically, clinical manifestations led to surgery with good evolution.