To determine the effect of an intervention program based on motor relearning on balance in adults with hemiparesis. Materials and methods: A quasi-experimental clinical trial was made in which 69 adults with hemiparesis participate, 34 in the control group and 35 in the experimental group, between 18 and 60 years of age. The control group received a program of conventional physiotherapeutic intervention and the experimental group a program of physiotherapeutic intervention based on the motor relearning model, for 6 weeks, 3 sessions / week. The pre-test and post-test measurements were performed in both groups using the Tinetti balance test and the analysis of the data with the SPSS statistical software. Results: After the intervention, both groups, the best overall measurement in the balance measured with the Tinetti scale, the difference between statistical significance between groups, the experimental embargo, the experimental group, the best performance in the performance of three of the items included. the Tinetti balance test: attempt to up from a chair, get up from a chair and push on the sternum, suggesting the positive influence of the motor relearning model on the balance necessary for the execution of the sit-down transition high bipedal and in the performance of the static equilibrium in biped. Conclusions: The intervention based on the model of motor relearning can be an effective approach within Neurorehabilitation, to improve the balance during the performance of functional activities in adults with hemiparesis between 18 and 60 years.