Glutamic acid is the key amino acid in living organisms. It was probably formed abiotically under conditions prevailing in early earth atmosphere and its two enantiomers have been found in meteorites. Eighteen of the amino acids found in proteins can be biosynthesized from it in different organisms. It is the main neurotransmitter in mammalian brain and it is an important commodity used in the food industry because of its unique taste. The two enantiomers, however, do not exhibit biological activity to the same extent. The Denantiomer usually has either very little or no activity as compared to the L enantiomer. In order to find an explanation for the differences, we have undertaken theoretical studies with classical and semi-empirical force field models on solvated Land D-glutamate.