Introduction: Assisted reproduction is based on any procedure that involves the manipulation of conception. Indistinctly of the intervention that patient and attendants agree to carry out, its purpose is to cause a pregnancy. This is the main idea that provided the ground for the principles of assisted reproduction for decades. However, nowadays it has been evidenced that the intention to provide gestational experience to our society, has generated a significant increase in the number of multiple-pregnancies; Conceptions that will have a greater risk of maternal and perinatal morbidity and mortality. Currently, there are educational models that have shown how the information and sensitization of the single versus multiple embryonic transfer within the usual clinical practice can achieve an impact in the reduction of the number of multiple pregnancies caused by assisted reproduction. Objective: This study aims to produce evidence on the impact of an educational model on the embryo transfer of patients taken to In-vitro fertilization in Reprotec, University Hospital Fundación Santa Fe de Bogotá, Colombia between 2016- 2017. : Quasi-experimental analytical transversal study with intra-subject comparison. The intervention is an educational program in single embryo transfer focused on population that required assisted reproduction techniques. The outcomes of interest were the number of embryos transferred, the perception of single versus twin pregnancies and the change in the intention of the number of embryos to be transferred. Results: 226 women and / or couples were included in the study. The group of women who were receptive to education was characterized by an age equal to or greater than 33 years, without previous abortions, but with a cycle of assisted reproduction, in whom the main diagnosis of infertility was mixed factors. The difference in proportions of the opinions before and after education was statistically significant concerning the number of offspring the woman or couple desire from the pregnancy (p: 0.041). Statistically significant differences were found in the women in whom 1 or two embryos were transferred for age, race, number of previous pregnancies, history of previous abortions, previous treatments of assisted reproduction and types of diagnoses (p: 0.000). Discussion: The women or couples of our study seem to be willing to make complex decisions if they are adequately informed, we have shown how factors such as age, the history of previous abortions and the number of assisted reproduction treatments influence the decision making of single or double embryo transfer; This is why we must work on strategies oriented to the profiles we have characterized in order to make clinical decisions that affect the infertile couple and their desire for a alive and healthy newborn. Conclusion: Education can be an effective strategy in reducing the number of embryos transferred in the cycles of assisted reproduction.