ImpactU Versión 3.11.2 Última actualización: Interfaz de Usuario: 16/10/2025 Base de Datos: 29/08/2025 Hecho en Colombia
Bioequivalence study of two 10 mg montelukast immediate-release tablets formulations: a randomized, single-dose, open-label, two periods, crossover study
A bioequivalence study was developed to compare the bioavailability of two formulations of Montelukast 10 mg tablets in twenty-four healthy volunteers. The Test product was Montelukast* manufactured by Tecnoquímicas SA (Jamundí–Colombia) and the Reference product was Singulair®(Montelukast) made by Merck Sharp & Dohme Ltd.(Northumberland-United Kingdom). A crossover design 2 x 2 of single-dose, with two treatments, two periods, two sequences and with a washout period of one week was used. Blood samples were
