The convective heat transfer process and flow characteristics of aluminum oxide (Al2O3)/water nanofluid flowing through milli channels with a hydraulic diameters of 2 mm, with a constant heat flux boundary condition, was investigated. Using experimental equipment, the effect of some factors like volume fractions, Reynolds number and Peclet number are evaluated. Furthermore, an experimental model for Nusselt number is presented in order to show the enhancement of the convective heat transfer compared with a single