Using P-wave travel time data from local seismicity, the crustal structure ofthe central and southern part of Colombia was determined. A very stableand narrow range of possible velocity models for the region was obtainedusing travel time inversion. This range of models was tested with earthquakelocations to select the best velocity model. The 1D velocity modelproposed has five layers over a halfspace, with interfaces at depths of 4, 25, 32, 40 and 100 km and P-wave velocities of 4.8, 6.6, 7.0, 8.0, 8.1 and 8.2 km/sec, respectively