In Colombia, approximately 11.8 million people live in rural areas, where most of them identify as indigenous, African descendant, Raizal, and Palenqueras communities (Machado & Botello, 2013). The 61.2% of these communities carry out the activities of production, transformation, and marketing under the family farming model (Zuluaga Cardona, Cuervo Cardona, & Diaz Granados, 2018). By 2010 such model represented the 67.3% of the agricultural production of the country, playing a crucial role in sustaining the national food security. However, many communities face distinct difficulties to commercialize their products (agricultural and handicraft). Consequently, there is a need to re-evaluate their cultural identity and organizational processes to make their production differentiated and recognized by their designation of origin. The commercial potential of the agricultural and livestock production systems of the reserve was evaluated based on the study "Fortalecimiento de la Soberanía Alimentaría Mediante la Recuperación del Patrimonio Cultural Agroalimentario de Los Pueblos Indígenas de Colombia” and data gathered from primary and secondary sources. Then, the feasibility and economic assessment of the aforementioned productive systems was performed, leading to a decision-making methodology for the positioning and marketing of the reserve products. As a result, the market niches with the highest likelihood of success were identified.