This paper presents the problem of redesigning a supply network of large scale by considering variability of the demand.The central problematic takes root in determining strategic decisions of closing and adjusting of capacity of some network echelons and the tactical decisions concerning to the distribution channels used for transporting products.We have formulated a deterministic Mixed Integer Linear Programming Model (MILP) and a stochastic MILP model (SMILP) whose objective functions are the maximization of the EBITDA (Earnings before Interest, Taxes, Depreciation and Amortization).The decisions of Network Design on stochastic model as capacities, number of warehouses in operation, material and product flows between echelons, are determined in a single stage by defining an objective function that penalizes unsatisfied demand and surplus of demand due to demand changes.The solution strategy adopted for the stochastic model is a scheme denominated as Sample Average Approximation (SAA).The model is based on the case of a Colombian company dedicated to production and marketing of foodstuffs and supplies for the bakery industry.The results show that the proposed methodology was a solid reference for decision support regarding to the supply networks redesign by considering the expected economic contribution of products and variability of the demand.