Introduction: about 90% of patients admitted to the intensive care unit (ICU) require invasive mechanical intubation during their stay. Symptoms such as anxiety and pain, allows assessing the subject´s adaptive capacity. Objective: to describe the applicability of the state-trait anxiety inventory (STAI), visual analog scale (VAS) and brief resilience scale (BRS) instruments in critical patients receiving invasive mechanical ventilation in the ICU of a high complexity hospital in Bogotá. Methodology: observational, descriptive, cross-sectional study. The STAI-6, EVA and BRS were used for data collection to evaluate anxiety, pain and resilience in adult patients who required invasive mechanical ventilation. The Stata 17 software was used to conduct a descriptive analysis. Results: of the 23 participants, 82.6% were women aged 24 to 84 years. Pain was rated as mild by 78.26% of patients on the pain scale. A high level of anxiety was experienced by 39.13% of patients, and in 60.86% resilience was found to be within the normal range. Conclusion: pain was the easiest sign to identify; the STAI-6 scale was useful and simple to apply to detect the anxiety level in ventilated critical patients; the BRS scale was not very specific and made understanding and assessment of resilience in mechanically ventilated patients, more complex.