The pathogenesis of sports injuries is complex and difficult to identify clearly. Recent theories bring to light new mechanisms related to the production of muscle pain and tendinopathies. The accumulation of lactate can cause fatigue and muscle pain. Apparently, the lactate anion is an excellent fuel for myocardial fibre. Its accumulation of lactic acid after performing intense physical exercise can prevent the excitability of the sarcolemma induced by the increase in the concentration of the interstitial potassium ion. The identification of sports and physical activity that can cause damage to our body has become necessary, due to the increase in the incidence of joint injuries generated by physical activity in people who routinely practice exercise and in athletes, in order to prevent future injuries. Articles related to the different mechanisms involved in the different musculoskeletal injuries related to the practice of exercise have been selected.