The objective of this article is to explore the possible obstacles, posed as challenges, that could arise for those who pursue the rights of protection of a designation of origin for coastal cheese made in the Colombian Caribbean Region. A review of the applicable legal framework is carried out, delving into the positive and negative criteria derived from what is enshrined in Andean Decision 486 of 2000, applied to a hypothetical request for protection that takes into account the real situation of coastal cheese producers. in this area of the country. From this, certain suggestions are proposed aimed at satisfying the positive requirements and avoiding the negative requirements, so that the intended protection can be achieved.