ABSTRACT Morphological abnormalities are rarely reported in night monkeys; in particular, eye problems in wild individuals are relatively rare in the literature. We present for the first time a record of corneal opacity in two wild individuals of the species Aotus lemurinus in the Andean region of Colombia. In this study, we found cases of corneal opacity probably associated with infectious and contagious processes, injuries resulting from attacks, the age of the individuals, and the health status of the groups in wildlife. We encourage researchers to report their observations of wild primates with ocular abnormalities, as this information could be useful in estimating rates of occurrence and addressing questions associated with the physiological status, social behavior of the species, and their effects on natural populations.