The objective of the study is to structure in an integrated way the quality management and occupational health and safety systems under the iso 9001:2015 and iso 45001:2018 standards applied to the transport company Intrapauto S.A.S, which shows the need to simplify documentation, avoid reprocessing and increase competitiveness; Three methodological phases are formulated, initially an organizational diagnosis is carried out regarding compliance with the requirements of these two standards, subsequently the integration method most in line with the needs of the company is selected and finally the integration of the management systems is designed. As a conclusion, the integration of quality management and occupational health and safety systems was obtained for Intrapauto S.A.S under the iso Handbook methodology, in order to increase the satisfaction of customers and other interested parties, improve the company's position in the sector and reduce implementation costs.