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Novel Directed Enzyme Prodrug Therapy for Cancer Treatment Based on 2′-Deoxyribosyltransferase-Conjugated Magnetic Nanoparticles

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Abstract:

Directed enzyme prodrug therapy (DEPT) strategies show promise in mitigating chemotherapy side effects during cancer treatment. Among these, the use of immobilized enzymes on solid matrices as prodrug activating agents (IDEPT) presents a compelling delivery strategy, offering enhanced tumor targeting and reduced toxicity. Herein, we report a novel IDEPT strategy by employing a His-tagged

Tópico:

Cancer Research and Treatments

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Citations: 2
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Información de la Fuente:

SCImago Journal & Country Rank
FuenteBiomolecules
Cuartil año de publicaciónNo disponible
Volumen14
Issue8
Páginas894 - 894
pISSNNo disponible
ISSNNo disponible

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