Carybdea xaymacana Conant, 1897 is a box jellyfish belonging to the family Carybdeidae and is currently recorded from the Mexican Caribbean (State of Quintana Roo), Puerto Rico, the Bahamas, Jamaica, Panama, and Venezuela. Here, we report for the first time the presence of this species in Colombia, based on collections made in three departments of the Colombian Caribbean. Documenting the extension in the distribution range of this species is of great importance due to its ecological role in regional ecosys-tems.